Fainting goats - Myotonia Congenita Disease

Recently my friend showed me a video about a certain breed of goats that are known for their frequent fainting. When they become starteled by something or get overly excited for food, their legs become stiff and they roll over onto their back. That is why they are nicknamed fainting goats or wooden leg goats.

This reaction is caused by a hereditary disease called Myotonia Congenita (Myotonia meaning the inability to relax voluntary muscle after vigorous effort and Congenita meaning present at birth.) This disease can relate to our class work because it is caused by a muation in the gene CLCN1 that is crutial for the movement of skeletal muscles. In a normal body, the protein produced by CLCN1 creates a ion flow that goes in and out of the muscles and allows normal muscle contractions. In a person or animal that has Myotonia Congenita, the mutation causes their ion flow to be much slower resulting in prolonges muscle contractions or severe muscle stiffness.